4-Benzyloxy-2-fluorophenylboronic acid

4-Benzyloxy-2-fluorophenylboronic acid - Names and Identifiers

Name	4-Benzyloxy-2-fluorobenzeneboronic acid
Synonyms	AKOS BRN-0077 4-Benzyloxy-2-fluorophenylboro 4-BENZYLOXY-2-FLUOROPHENYLBORONIC ACID 4-Benzyloxy-2-fluorophenylboronic acid 4-BENZYLOXY-2-FLUOROBENZENEBORONIC ACID 4-Benzyloxy-2-fluorobenzeneboronic acid 4-Benzyloxy-2-fluorophenylboronic Acid (contains varying amounts of Anhydride)
CAS	166744-78-1
EINECS	672-875-2
InChI	InChI=1/C13H12BFO3/c15-13-8-11(6-7-12(13)14(16)17)18-9-10-4-2-1-3-5-10/h1-8,16-17H,9H2

4-Benzyloxy-2-fluorophenylboronic acid - Physico-chemical Properties

Molecular Formula	C13H12BFO3
Molar Mass	246.04
Density	1.26±0.1 g/cm3(Predicted)
Melting Point	151 °C
Boling Point	406.8±55.0 °C(Predicted)
Flash Point	199.8°C
Vapor Presure	2.4E-07mmHg at 25°C
pKa	8.50±0.58(Predicted)
Storage Condition	Inert atmosphere,2-8°C
Refractive Index	1.577
MDL	MFCD02093064

4-Benzyloxy-2-fluorophenylboronic acid - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
Hazard Note	Irritant/Keep Cold
Hazard Class	IRRITANT, KEEP COLD

4-Benzyloxy-2-fluorophenylboronic acid - Introduction

Icid, also known as 2-fluoro-4-methoxyphenylboronic acid, is an organic boron compound. The following is a description of some properties, uses, preparation and safety information about the compound:

Nature:
-Appearance: White to light yellow solid.
-Solubility: Soluble in common organic solvents such as alcohols, ethers and ketones.
-Melting point: About 40-45 ° C.
-Molecular formula: C13H12FO2B.

Use:
-acid is commonly used as a reagent and catalyst in organic synthesis.
-It can be used for the functionalization reaction of benzene ring, such as the coupling reaction of aromatic alkyne and borate.

Method:
-or acid can be obtained by the reaction of benzyl alcohol and 2-fluorophenylboronic acid under appropriate conditions.
-The reaction is usually carried out under an inert atmosphere and at room temperature, using an anhydrous organic solvent as the reaction medium.
-The preparation process requires certain operating skills and laboratory equipment.

Safety Information:
-This compound is an organic boron compound. You need to pay attention to safety measures when using it, such as wearing gloves and goggles.
-Avoid inhaling dust or contact with skin and eyes.
-When used indoors, provide a good ventilation system.
-Avoid reacting with strong oxidants and strong acids.
-Keep sealed during storage and avoid humid and high temperature environments.
-Before use and storage, carefully read the safety data sheets of chemicals and follow relevant safety procedures.

Last Update：2024-04-10 22:29:15